Humanized NSG and NSG-SGM3 mice as a new preclinical bridge for immune-oncology therapies
Humanized NSG and NSG-SGM3 mice as a new preclinical bridge for immune-oncology therapies.
In this guide you will find:
- Evidence that humanized NSG mice can support the growth of allogeneic human tumors
- Human tumors respond to standard-of-care chemotherapeutics and to immune check-point inhibitors clinically proven to initiate cytotoxic activity towards the tumor
- Tumor-bearing, humanized NSG mice are a new and valuable preclinical testing platform for immuno-oncology
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