Remote Bioprocess Monitoring with BioNsight® cloud: Every run in one view, from 100 mL development to production

Bioprocess data becomes valuable at the moment it can be compared. Results from a run in a small parallel system, a run at bench scale, and a run in another building are usually held in separate files, and the comparison happens by hand long after it would have been useful. BioNsight cloud brings those runs together in one browser view, so a process can be followed while it is running and examined against earlier runs once it is finished.

BioNsight cloud connects to Eppendorf bioprocess systems through DASware control and holds the process data of each run with its context. Users can follow a running process from their desk or from another site, and colleagues in different locations can look at the same data during a discussion instead of exchanging exports. The value shows most clearly when a process moves between scales: runs from different vessel sizes can be placed next to each other, so the effect of a process change is visible rather than inferred. Eppendorf applications scientists used this to optimize pH in a CHO cell culture process, where the comparison between runs and scales is what made the optimization manageable.

The same software family carries the process as it grows. DASware control runs across Eppendorf bioreactor systems from 100 mL process development upward, and DASware control plus supports GMP requirements where development and clinical supply are regulated, so the monitoring approach does not change when the volume does. Behind it sits more than three decades of developing and supporting software designed for upstream bioprocess.

To learn more about BioNsight cloud and remote bioprocess monitoring, visit: https://eppendorf.group/49fodj3k