An invasive front of highly aggressive tumour cells (in green). Confocal microscopy image. © Alexandra Avgustinova, IRB Barcelona

Researchers at IRB Barcelona report that tumours may become more aggressive following treatment with drugs that inhibit epigenetic factors.

EB_Autumn_2018_Guenter_Huhle.jpg

In February, Johnson & Johnson Innovation, JLABS opened its first European open innovation incubator, JLABs @ BE, at the heart of the Beerse Janssen R&D Campus in Belgium. European Biotechnology spoke with Günter Huhle, Head of Johnson & Johnson Innovation JLABS EMEA, about Johnson & Johnson‘s approach to open innovation and its tremendous global innovation network, currently comprising ten incubators and over 420 companies that have collectively raised over US$10bn in growth capital.

MCC950 blocks the activation of the NLRP3 inflammosome. © Inflazome

Inflammosome inhibitor specialist Inflazome Ltd has raised €40m in a Series B financing led by Forbion with co-investors Longitude Capital, Novartis Venture Fund and Fountain Healthcare Partners.

The European Commission's Chief Scientific Advisors presented a review of "New Techniques in Agricultural Biotechnology" in 2017. © EC

The EU Commission’s Chief Scientific Advisors urge the Commission to revise the EU’s GMO Directive in order to harness gene editing.

Eppendorf

The flexible BioFlo 120 bioreactor/fermentor control station is capable of microbial fermentation as well as mammalian cell culture applications. 

© 123rf.com/ ktsdesign

Boehringer Ingelheim and Epizyme, Inc. will collaborate in the field of small molecule cancer drugs that target unaddressed epigenetic targets within the helicase and histone acetyltransferase families.

© 123rf.com/Sorapop Udomsri

Researchers at University of Göttingen, Germany, have identified nerve excitability of motor nerve cells trigger restless legs syndrome.

Karl Keegan. Picture: Nox Therapeutics

Hox Therapeutics has announced the appointment of Dr Karl Keegan as Chief Executive Officer.

Human respiratory syncytial virus, HRSV. Transmission electron microscopy, negative staining. Bar = 200 nm. © Hans R. Gelderblom (2002)/RKI

AstraZeneca plc has sold US rights to its off-patent blockbuster drug Synagis (palivizumab) and a 50% share on future earnings of its Phase II RSV-prophylactic follow-on antibody MEDI8897 to Swedish Orphan Biovitrum AB.  

MoA of Amal's cancer vaccines. © Springer Link, Cellular and Molecular Life Sciences

Swiss Amal Therapeutics S.A. (Geneva) has raised €21.2m in a series B follow-up financing.