© Themis Bios­cience GmbH

One week after Austrian vaccine and cancer immunotherapy specialist Bioscience announced the terms of its initial public offering (IPO) and listing on Euronext Amsterdam, the company has postponed its IPO.

The vision of the new approach is to awake T effector cells through BH4, which antagonises mediators of the immunosuppressive tumorr microenvironment, to fight cancer. © IMBA

Researchers at Austrian IMBA have identified a well-known co-factor of amino acid synthesis and monoamine neurotransmitter synthesis to play a prominent role in the development of autoimmunity and cancer.

BIO-Europe networking party in Copenhagen. © BIOCOM AG

Gene and cell therapies, pediatric drugs, and formulation were just some hot topics discussed in a record number of B2B meetings at BIO-Europe in Copenhagen. 

Oxurion NV and Beta Therapeutics Inc have inked an R&D agreement aimed to develop new heparanase inhibitors to treat dry AMD.

Schematic of the three-step targeted delivery procedure used for the slippery micropropellers.
(1) Injection of the micropropellers into the vitreous humor of the eye. (2) Magnetically driven long-range propulsion of the micropropellers in the vitreous toward the retina. (3) Observation of the micropropellers at the target region near the surface of the retina by OCT.

German researchers have developed a drug delivery nanobot that can propel through the eye.

ARGX-110 mode of action. © Argenx SE
Argenx SE announced it achieved an overall response rate of 92% in patients with AML with its anti-TNFSF7 (CD70) antibody cusatuzumab. 
Denali Therapeutics raised $250m through an Nasdaq IPO in December 2017. © Nasdaq

Sanofi has acquired the global commercialisation rights for two preclinical programmes from Denali Therapeutics.

Dutch ProQR NV has licensed global commercialisation rights to IONIS-RHO-2.5Rx (QR-1123) from Ionis Pharmaceuticals, to treat autosomal dominant retinitis pigmentosa (adRP)

The EIB has agreed to support Italian CNS drug developer Newron Pharmaceuticals with up to €40m to support the development of the company’s late-stage pipeline.

© TES Pharma SRL

TES Pharma has presented a novel treatment approach for acute kidney injury and non-alcoholic fatty liver disease in Nature.