Postulated mechanisms of mortality in sepsis. © Sphingotec GmbH

Critical care experts have presented data supporting the thesis that three specific pathways are the cause for about 90% of sepsis mortality.

P. aeruginosa. © CDC

Antabio SAS has got a US-$4.4m tranche from CARB-X to advance preclinical development of its P. aeruginosa treatment in Cystic Fibrosis patients

© Pixabay/Hans Braxmeier

Swedish and Danish researchers have created a hydrogel that kills various types of bacteria and reduces inflammation in mice and pigs with infected wounds.

© Oxford Biodynamics

The technology of Oxford-based Oxford Biodynamics (OBD) promises insights into why immunotherapies only work in some patients but not in all. A major US pharma company now wants to validate OBD’s epigenetic biomarker discovery and development platform causing a share price gain of 15%.

© Beata Dudová/Pexels

Paris-based European venture capital company Truffle Capital closed its €250m BioMedTech fund – celebrating its company building approach.

Mode of action of CB-103
© Cellestia

Basel-based biopharma company Cellestia Biotech AG has successfully closed a Series B financing round, raising a total of CHF 20 million.

Sphingotec headquarters, © Sphingotec GmbH

Data from 1,200 heart failure patients demonstrate that high discharge levels of the biomarker bio-ADM® (bioactive Adrenomedullin) indicate residual congestion in heart failure patients.

© VIB

The new company, named Augustine Therapeutics, is a Vlaams Instituut voor Biotechnologie (VIB) and Katholieke Universiteit (KU) Leuven spin-off. Funded with €4.2m from mainly local investors, Augustine’s first priority is finding new therapeutics for patients suffering from Charcot-Marie-Tooth disease, a hereditary motor and sensory neuropathy of the peripheral nervous system.

Transgene's CEO Philiippe Archinard. © Transgene SA

French Transgene SA said it has terminated its lead programme TG4010 in combination with chemotherapy and checkpoint inhibition. 

Inflamed hair follicles during EGFR inhibition.© Jo?rg Klufa and Thomas Bauer, Medical University Vienna

New research demonstrates that disruption of EGF receptor signalling allows commensal bacteria to invade hairs and cause skin lesions.