Dual mode of action: APN01 blocks virus entry and the ARDS-associated inflammation. Picture: Apeiron Biologics AG

Viennese APEIRON Biologics AG raised €17.5m to expand ongoing Phase II trials of its
coronavirus-specific drug candidate APN01 in Europe to the US and Russia. The recombinant angiotensin-converting enzyme 2 (rhACE2) mimics the receptor on the human cells that coronaviruses are using to infect these cell. Preclinical and clinical data demonstrate that APN01 is well-tolerated and can stop the overshooting host immune responses that are triggered by virus proliferation.

Current quantitative COVID-19 antibody tests are often research-only tests. Quantitative assays may inform researchers about the antibody blood level that might be virus-neutralising. Currently it is open if there are virus-neutralising antibody levels in the blood of humans. © Siemens Healthineers

In a Public England Health study, Siemens Healthineers’ COV2T antibody test was the only assay found to meet both sensitivity and specificity requirements of the MHRA.

On 9th July a broad coaltion of pharma assocations, pharma CEOs, policy makers and AMR experts launched a new global intiative to fight antbiotic resistance in a virtual event series in Berlin, Washington and Tokyo. © BIOCOM AG

After leaving the field of antimicrobials 20 years ago because other areas offered better returns, 23 pharma companies and the Novo Foundation have launched a US$1bn fund to fight antimicrobial resistance (AMR).

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Leiden-based coagulant developer VarmX NV has closed a €32m Series B financing to push clinical development of VMX-C001, a venom-based modified recombinant Factor X.

Preparation of APN401. © APEIRON Biologics AG

Viennese APEIRON Biologics and MaxCyte Inc have entered into licensing agreement covering the use of Maxcyte’s electroporation platform for APN401 development.

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After closing the business merging with blank check company Arya Sciences Acquisition Corp, Immatics Inc has been listed on Nasdaq.

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A new insulin formulation allows patients with diabetes to more quickly manage their blood sugar levels during mealtimes.

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Data from the UK’s RECOVERY trial demonstrate there was no clinical benefit from use of lopinavir-ritonavir in hospitalised COVID-19 patients.

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Under the Coronavirus Global Response Framework, the European Commission is allocating further €4.9bn to assure access to COVID-19 countermeasures for poor countries.

© Kevin Schneider/Pixabay.com

BioGeneration Ventures has closed its fourth VC fund for European start-ups (BGV IV) at €105m.