Accelerating and derisking antibody drug development by early lead panel optimization. Picture:©Yumab GmbH

Antibody engineering?The development of therapeutic antibodies is a time and cost ­intensive process. Biological and physicochemical properties of the lead molecules ­influence almost every step in the development. Investing into antibody engineering and lead ­optimisation during early development pays off in later steps and does not only accelerate the programme, but also increases the chance of success.

© Dewpoint Therapeutics

German Evotec SE and  Boston-based Dewpoint Therapeutics Inc have entered into a strategic partnership in oncology.

Oncopole Toulouse. © Don-vip - wikipedia.org

Pierre Fabre Laboratories SA has extended its global partnership with Atara Biotherapeutics, licencing tabelecleucel commercialisation rights for Northern America and beyond.

©Quince Creative - pixabay.com

Biotech companies in Scotland’s thriving bio-based manufacturing have been invited to apply for up to £1m funding within the Launchpad programme.

© Memo Therapeutics AG

Swiss Memo Therapeutics AG will use CHF25m raised in a new Series C financing to complete a Phase II study with Anti-BKV for prevention of virus-induced graft damage.
 
   

Christina Lohmeyer und Sasa Ilic (SUNBEAM VISION OHG)

Researchers led by Wolfgang Enard from LMU Munich have identified a microRNA-based mechanism that drives atherosclerosis by weakening the integrity of blood vessel walls.

Christoph Schröder, CEO Sciomics GmbH and Arantxa Encinas-Lopéz, BioRN

Due to the global niche character of pharmaceutical biotechnology, research collaborations and market entries on an international level are essential. Agility and market ­knowledge are ­required to maintain an overview in a rapidly evolving environment and to initiate a ­sustainable internationalisation process.

Picture: © Northway Biotech

When businesses receive a proposal from a contract development and manufacturing organisation (CDMO), it’s much like a first date: first impressions matter. The proposal process not only reveals a CDMO’s services but also hints at the potential relationship’s quality. This is gauged mainly through metrics like timing, quality, and price.

Cellectis' TALEN technology. © Cellectis SA

AstraZeneca plc has paid French cancer cell therapy developer Cellectis SA US$25m upfront and US$220m in equity in an US$2.2bn R&D deal for up to ten cell and gene therapies.

© NICCOLO BIDDAU/ALFASIGMA

Italian pharma company Alfasigma SpA has signed  a letter of intent to acquire the filgotinib business from Galapagos.