
New risk factor for autism and epilepsy identified
The KCC2 K+Cl– co-transporter is critical for the health and maturity of neurons, as it helps to maintain a low concentration of chloride ions in...

NSCLC: Bemcentinib + anti-PD1 triple PFS
Bergen Bio ASA announced the primary endpoint of 25% Overall Response Rate (ORR) has been met in predominantly PD-L1 negative/low NSCLC patients in a...

4SC expands domatinostat combo testing
In an investigator-initiated Phase Ib study (DONIMI) at NKI, 40 patients with melanoma will be enrolled before surgery (neoadjuvant setting) to...

Novo Nordisk enters haemophilia gene therapy field
Changes in the treatment standard of haemophilia A, such as Roche’s 2017 launch of Hemlibra, have put Novo Nordisk’s revenues (in the US$15.8bn...

EMA greenlights new medicines
With the three innovative medicines and four generics the number of recommended medicines raised to 47 in 2019. The Committee saw a positive...

New malaria lead kills 99.9% of pathogens
The researchers built on the fact, that Plasmodium is highly dependent on external supply and metabolisation of vitamin B 5 (pantothenamide). They...

Lundback swallows migraine drug maker Alder
Alder's first-in-class monoclonal antibody for migraine prevention, eptinezumab, targets the calcitonin gene-related peptide and faces FDA...