Tag Archive for: macrophage

Treatment with the agonistic TREM2 antibody 4D9 leads to the formation of smaller necrotic cores (red outlines) in atherosclerotic plaques of the aortic root in Ldlr-/- mice. © Nature Cardiovascular Research

TREM2, a receptor on the surface of macrophages, reduces necrotic core formation in early atherosclerosis, a German-Austrian reseach team reports.

© Ono Pharmaceuticals Co Ltd

Edinburgh-based immuno-oncology expert Macomics Ltd has partnered with Ono Pharmaceutical to develop a macrophage-targeting antibody targetting cancer.